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AMBERCHROM™ XT Resins

Reversed Phase Chromatographic Resins

for Biomolecule Purification and Polishing

 

 

AMBERCHROM™ XT chromatographic media are a refinement of the existing AMBERCHROM™ CG line offering higher pressure capabilities, improved resolution and the same stability to caustic CIP procedures. They are targeted for biomolecule purification and address the needs of the customer for an economical alternative to silica in their reversed phase chromatographic protocols. AMBERCHROM™ XT media have demonstrated exceptional in purifying hydrophobic and polar peptides, small proteins and oligonucleotides. They are ideally suited for therapeutic proteins such as insulin.

 

Downstream purification can be optimized by taking advantage of their excellent pH stability in purifying a wide range of peptides and oligonucleotides, which means higher plant productivity at lower cost. The resolving power of AMBERCHROM™ XT delivers high yield-purity in the separation, and their superior rigidity permits use with medium pressure equipment, up to 60 bar.

Available in two different particle size ranges (20 and 30 microns) AMBERCHROM™ XT are compatible with most organic solvents, dilute acids and bases.

 

AMBERCHROM™ XT30 is ideal for front end capture from fermentation or synthesis procedures,

AMBERCHROM™ XT20 provides the resolution and purity required for final product polishing steps in the purification train.

 

 

Amberchrom XT Resin Properties

 

 

Matrix

 

        Polystyrene/divinyl benzene

Bead Form

        Spherical, macroporous

Pore Size

        300 Å

Particle Size

        Amberchrom™ XT20 – 20 µm

 

        Amberchrom™ XT30 – 30 µm

Maximum Pressure

        60 bar

pH Stability

        1 – 14

Operating Temperature

 

        4 – 60° C

 

 


Related Literature:

• Amberchrom™ XT product data sheet (A4 - US letter)

• Amberchrom™ XT20 MSDS (UK English - US English)

• Amberchrom™ XT30 MSDS (UK English)

Amberchrom™ XT technical bulletin (pdf - file size 870 ko)
   

 

 

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