AMBERCHROM™ XT Resins Reversed Phase Chromatographic Resins for Biomolecule Purification and Polishing

AMBERCHROM™ XT chromatographic media are a refinement of the existing AMBERCHROM™ CG line offering higher pressure capabilities, improved resolution and the same stability to caustic CIP procedures. They are targeted for biomolecule purification and address the needs of the customer for an economical alternative to silica in their reversed phase chromatographic protocols. AMBERCHROM™ XT media have demonstrated exceptional in purifying hydrophobic and polar peptides, small proteins and oligonucleotides. They are ideally suited for therapeutic proteins such as insulin.

Downstream purification can be optimized by taking advantage of their excellent pH stability in purifying a wide range of peptides and oligonucleotides, which means higher plant productivity at lower cost. The resolving power of AMBERCHROM™ XT delivers high yield-purity in the separation, and their superior rigidity permits use with medium pressure equipment, up to 60 bar.

Available in two different particle size ranges (20 and 30 microns) AMBERCHROM™ XT are compatible with most organic solvents, dilute acids and bases:

AMBERCHROM™ XT30 is ideal for front end capture from fermentation or synthesis procedures,

AMBERCHROM™ XT20 provides the resolution and purity required for final product polishing steps in the purification train.

Amberchrom™ XT Resin Properties
Matrix	Polystyrene/divinyl benzene
Bead form	Spherical, macroporous
Pore size	300 Å
Particle size	Amberchrom XT20 - 20 µm
	Amberchrom XT30 - 30 µm
Maximum pressure	60 bar
pH stability	1 - 14
Operating temperature	4 - 60°C

Additional Information

Amberchrom™ XT product data sheet (A4 - US letter)

Amberchrom™ XT technical bulletin (pdf - file size 870 ko)